Humanized Mice in Dermatology Research
نویسندگان
چکیده
منابع مشابه
Humanized mice
Animal models have been instrumental in increasing the understanding of human physiology, particularly immunity. However, these animal models have been limited by practical considerations and genetic diversity. The creation of humanized mice that carry partial or complete human physiological systems may help overcome these obstacles. The National Institute of Allergy and Infectious Diseases con...
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Regulatory T cells (Treg) control immune cell function as well as non-immunological processes. Their far-reaching regulatory activities suggest their functional manipulation as a means to sustainably and causally intervene with the course of diseases. Preclinical tools and strategies are however needed to further test and develop interventional strategies outside the human body. "Humanized" mou...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2015
ISSN: 0022-202X
DOI: 10.1038/jid.2015.393